Anything that doesn't break our terms and conditions (basically anything that could get us into legal trouble) and isn't individually attacking or being invasive towards another user .
yoomoot's strength is in handling large and complex discussions with many tangents, so we particularly encourage questions that lead to those kind of discussions. For example, acm has asked some great questions.
But any kind of question is very welcome. I just can't claim that Yoomoot is any better than standard Q&A sites for them :)